CHRONIC CHEMOGENETIC ACTIVATION OF HIPPOCAMPAL PROGENITORS ENHANCES ADULT NEUROGENESIS AND MODULATES ANXIETY-LIKE BEHAVIOR AND FEAR EXTINCTION LEARNING

Chronic chemogenetic activation of hippocampal progenitors enhances adult neurogenesis and modulates anxiety-like behavior and fear extinction learning

Adult hippocampal neurogenesis is a lifelong process that involves the integration of newborn neurons into the hippocampal network, and plays a role in cognitive function and the modulation of mood-related behavior.Here, we sought to address the impact of chemogenetic activation of adult hippocampal progenitors on distinct stages of progenitor deve

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Polymorphism in the tyrosine hydroxylase (TH) gene is associated with activity-impulsivity in German Shepherd Dogs.

We investigated the association between repeat polymorphism in intron 4 of the tyrosine hydroxylase (TH) gene and two personality traits, activity-impulsivity Wheelchair and inattention, in German Shepherd Dogs.The behaviour of 104 dogs was characterized by two instruments: (1) the previously validated Dog-Attention Deficit Hyperactivity Disorder R

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